<status value="draft"/> <experimental value="false"/> <date value="2026-08-07T08:41:18-04:00"/> <publisher value="UNICEF"/> <contact> <name value="UNICEF"/> <telecom> <system value="url"/> <value value="https://www.unicef.org"/> </telecom> </contact> <description value="WHO/CIOMS criteria that make an adverse event SERIOUS — the reason behind AdverseEvent.seriousness = serious. Intervention-neutral (AEFI and MDA pharmacovigilance) (espen-v4 / §17.2 C1)."/> <jurisdiction> <coding> <system value="http://unstats.un.org/unsd/methods/m49/m49.htm"/> <code value="001"/> <display value="World"/> </coding> </jurisdiction> <caseSensitive value="true"/> <content value="complete"/> <count value="6"/> <concept> <code value="death"/> <display value="Results in death"/> <definition value="The event resulted in death."/> </concept> <concept> <code value="life-threatening"/> <display value="Life-threatening"/> <definition value="The event was life-threatening."/> </concept> <concept> <code value="hospitalization"/> <display value="Requires/prolongs hospitalization"/> <definition value="Required inpatient hospitalization or prolonged an existing stay."/> </concept> <concept> <code value="disability"/> <display value="Persistent / significant disability"/> <definition value="Resulted in persistent or significant disability/incapacity."/> </concept> <concept> <code value="congenital-anomaly"/> <display value="Congenital anomaly / birth defect"/> <definition value="Resulted in a congenital anomaly/birth defect."/> </concept> <concept> <code value="medically-important"/> <display value="Other medically important event"/> <definition value="A medically important condition not otherwise listed (clinical judgement)."/> </concept> </CodeSystem>

Generated Narrative: CodeSystem icr-serious-criteria-cs

This case-sensitive code system https://icr.healthcampaigns.org/CodeSystem/icr-serious-criteria-cs defines the following codes:

Code	Display	Definition
death	Results in death	The event resulted in death.
life-threatening	Life-threatening	The event was life-threatening.
hospitalization	Requires/prolongs hospitalization	Required inpatient hospitalization or prolonged an existing stay.
disability	Persistent / significant disability	Resulted in persistent or significant disability/incapacity.
congenital-anomaly	Congenital anomaly / birth defect	Resulted in a congenital anomaly/birth defect.
medically-important	Other medically important event	A medically important condition not otherwise listed (clinical judgement).